December 1st, 2023

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Heterotopic Pregnancy with Intrauterine Partial Hydatidiform Mole and a Tubal Ectopic A Case Report
Authors:  Laura C. Gemmell, M.D., and Jeffrey M. Goldberg, M.D.
BACKGROUND: The co-occurrence of a spontaneous heterotopic pregnancy involving a partial hydatidiform mole is exceptionally rare and poses unique diagnostic challenges.

CASE: A 33-year-old woman underwent a suction dilation and curettage for evacuation of a spontaneously conceived partial molar pregnancy. She presented with pelvic pain and rising human chorionic gonadotropin (hCG) levels 7 weeks later. A right ampullary ectopic pregnancy was discovered and treated by laparoscopic salpingostomy, with progressive decline of her hCG levels.

CONCLUSION: This case is presented not only for the rarity of the co-occurrence of a heterotopic intrauterine partial molar and tubal ectopic pregnancy, but also as a reminder to consider the possibility of this entity with rising hCG levels following evacuation of a molar pregnancy prior to initiating treatment for persistent gestational trophoblastic disease.
Keywords:  chorionic gonadotropin, ectopic pregnancy, gestational trophoblastic disease, heterotopic pregnancy, hydatidiform mole
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