June 30th, 2022

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Title:
Retrospective Analysis of Spontaneous Pregnancy Cases After in Vitro Fertilization Six Years of Experience
Authors:  Nur Dokuzeylul Gungor, M.D., Tugba Gurbuz, M.D., Arzu Yurci, M.D., and Ergul Demircivi Bor, M.D.
  OBJECTIVE: To examine the clinical features of cases with spontaneous pregnancy after successful or unsuccessful in vitro fertilization (IVF).

STUDY DESIGN: IVF procedures performed in 2 IVF clinics between October 2014 and November 2020 were retrospectively analyzed. Ninety-five cases that conceived spontaneously after IVF treatment were included in the study.

RESULTS: The mean age was 32.07±4.52 years, and the mean duration of infertility was 4.37±2.05 years. The etiology of infertility was PCOS in 36.84%, unexplained infertility in 33.68%, endometriosis in 11.58%, and PCOS+endometriosis in 11.58% of patients. Records showed that 8.42% of the cases had undergone laparoscopy and 16.84% had undergone hysteroscopy. The number of IVF attempts was 1 in 52.63% of the cases, and the outcome was negative in 31.58% of the cases. Among those with pregnancy after IVF, 64.21% resulted in a live birth. The period from the IVF procedure to spontaneous pregnancy was shorter than 3 years in 97.89% of the cases.

CONCLUSION: The frequency of PCOS, unexplained infertility, and endometriosis diagnoses among those who had later conceived spontaneously was quite high. It appears that prolonging waiting time for spontaneous pregnancy in such cases can prevent unnecessary IVF procedures.
Keywords:  assisted reproductive technologies, endometriosis, in vitro fertilization, infertility, polycystic ovary syndrome, spontaneous pregnancy, unexplained infertility
   
   
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