December 7th, 2021

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Title:
Evaluating the Efficacy of Surgical Site Infection Prevention Bundle for Cesarean Delivery: A Retrospective Cohort Study
Authors:  Catherine Callinan, M.D., Bryan Knepper, M.P.H., Deborah Aragon, M.P.H., Kent Heyborne, M.D., Meredith Alston, M.D., Karen A. Ryall, Ph.D., and Stefka Fabbri, M.D., M.P.H.
  OBJECTIVE: To evaluate the impact of the implementation of a surgical site infection prevention bundle on the prevalence of surgical site infections and wound complications in cesarean delivery for up to 6 weeks postoperatively.

STUDY DESIGN: A retrospective cohort study was conducted for all patients undergoing cesarean delivery for any indication between November 2016 and December 2018. A surgical site infection prevention bundle was implemented. The primary outcome was a composite of surgical site infections and wound complications within 6 weeks after the procedure.

RESULTS: After the bundle implementation, there was significant reduction in the primary composite outcome of surgical site infections and wound complications by 56% (8.5% [65/769] vs. 3.7% [29/781]; adjusted odds ratio 0.378, 95% confidence interval 0.233–0.597) with number needed to treat of 21.

CONCLUSION: The implementation of an evidence-based surgical site infection prevention bundle significantly decreased the prevalence of surgical site infections and wound complications after cesarean delivery.
Keywords:  anti-infective agents; antibiotic prophylaxis; cesarean section, adverse effects; postoperative care; pregnancy; subcutaneous fat, surgery; surgical site infection; surgical wound dehiscence; surgical wound infection; therapeutic irrigation; treatment outcome; wound closure techniques
   
   
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