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Title: |
High-Dose Palliative Radiation Therapy for Solitary Recurrence of Ovarian Cancer in the Brain: A Case Report | |||||||||||||||||||
| Authors: | Alex Y. Chen, M.D., Ph.D., Jessica K. Sassic, B.S., Mazen Mislmani, M.D., and Anna V. Hoekstra, M.D., M.P.H. | |||||||||||||||||||
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BACKGROUND: Brain metastases from ovarian cancer are rare and are associated with a poor prognosis. CASE: A 53-year-old woman presented with stage IIIC high-grade serous ovarian cancer. Nineteen months later, new neurologic symptoms led to a diagnosis of oligometastatic brain recurrence. She was treated with subtotal resection and declined adjuvant therapy, leading to a rapid regrowth of the tumor with a significant midline shift. She received urgent, aggressive partial brain radiotherapy. She has been without evidence of disease for 44 months since recurrence. CONCLUSION: Aggressive multimodality therapy may be considered in patients with metastatic ovarian cancer to the brain. |
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| Keywords: | brain metastases, ovarian cancer, palliative treatment, radiation therapy, surgery | |||||||||||||||||||
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