June 30th, 2022

Mitochondria Transplantation: Why?
Authors:  Hakan Öztürk, M.D.
  To the Editors:
Mitochondria transplantation, i.e., mitochondria donation, is one of the most current topics in reproductive biology. For many years scientists have focused on the acquisition of genetic material from an organism’s own parents—i.e., “vertical transfer”—and have made progress in treatment of familial genetic diseases and associated genes. However, horizontal transfer recently has been recognized as a significant concept. Horizontal gene transfer (HGT), also known as lateral gene transfer, is defined as any process that results in the acquisition of a genetic material of a second organism without being reproduced from the organism. The transfer of the second genetic data implies the presence of 3 different genetic structures in the bearing cell, which in turn corresponds to offspring with 3 parents.
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