August 2nd, 2021

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A Note from the Editor-in-Chief
Authors:  L. D. Devoe, M.D.
  Welcome to the May-June 2011 Editor-in-Chief’s page. In this issue I will focus on two studies related to important areas in clinical gynecology.

In This Issue:

• Clinical Usefulness of Contrast-Enhanced Color Doppler Ultrasonography in Invasive and Noninvasive Gestational Trophoblastic Diseases: A Preliminary Study
M. Emoto, R. Sadamori, T. Hachisuga, T. Kawarabayashi and S. Miyamoto

While most gestational trophoblastic disease (GTD) is fortunately benign and augurs good outcomes using standard surgical and medical therapies, recognition of more aggressive lesions prior to treatment has always been of major concern. As there are significant consequences following both under- and overtreatment, any technique that permits better distinction of the more serious GTDs such as choriocarcinoma and invasive mole would be welcome. Emoto and coauthors have evaluated a relatively recent imaging technique that couples color Doppler ultrasonography (CDU) with contrast enhancement provided by microbubble contrast agents. In this limited series of 23 patients, all of those with malignant or invasive GTDs were correctly characterized by increased vascular flow captured by contrast-enhanced CDU, while those with noninvasive disease lacked these ultrasound findings. Importantly, small lesions (less than 2 cm) within the myometrium were identified. This hybrid imaging technique, which has been used successfully in echocardiography, is now being applied to other tissues of interest. Hopefully, this study will encourage the authors and others to pursue this line of investigation with larger cohorts.
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