June 30th, 2022

A full text version of this article is available.
To access article obtain online access here or login
Effect of Patient Age on Outcomes and Compliance in Women with Minimally Abnormal Pap Tests
Authors:  J. S. Carter, M.D., Y. Hoffman Sage, M.D., M.P.H., O. Vragovic, M.B.A., L. Rosen, M.S.E.E., and E. A. Stier, M.D.
  OBJECTIVE: To assess follow-up and histologic outcomes by age for an indigent urban cohort of women with minimally abnormal cytology.

STUDY DESIGN: Retrospective analysis of Pap tests was performed (January 2, 2002, to June 30, 2005). Adolescents (age <21) and women with atypical squamous cells of undetermined significance (ASCUS)/high-risk human papillomavirus (HPV) and low-grade squamous intraepithelial lesions (LSIL) Pap results were studied and followed for outcomes at 2 years. The c2 test was performed to evaluate differences among groups; statistical significance was established as p?0.05.

RESULTS: A total of 2,266 women were studied—676 adolescents, 1,063 women aged 21–30 years, and 527 women >30 years of age. Results included 619 ASCUS/ high-risk HPV and 1,647 LSIL results. Compliance was similar across age-groups; 31% never returned for
follow-up. CIN2 was detected in 18.8% of adolescents, 21.6% of women aged 21–30, and 15.7% of women >30 years (p=0.53). CIN3 was detected in 8.5% of adolescents, 8.1% of women aged 21–30, and 7.7% of women >30 years (p=0.55).

CONCLUSION: Adolescents and women had similar rates of loss to follow-up after having a minimally abnormal Pap test. The likelihood of detecting CIN2-3 was similar regardless of age.
Keywords:  atypical squamous cells of undeter- mined significance, cervical intraepithelial neoplasia, colposcopy, compliance, human papilloma virus, low-grade squamous intraepithelial lesion
  Acrobat Reader 7.0 is recommended to properly view and print the article.
Reader can be downloaded from