May 29th, 2022

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Geographical Distribution and Demographic Characteristics of Gestational Trophoblastic Disease
Authors:  P. D. P. B. Soares, M.D., I. Maestá, M.D., O. L. N. Costa, M.D., R. C. Charry, M.D., A. Dias, Ph.D., and M. V. C. Rudge, M.D.
  OBJECTIVE: To outline the geographical distribution pattern of gestational trophoblastic disease (GTD) in a referral center in Bahia, Brazil, and determine the demographics of the disease.

STUDY DESIGN: We conducted a study of data retrieved from medical records of 140 GTD patients referred to our Trophoblastic Diseases Center in 2002–2007, assessing geographical distribution across health care districts, demographics, referral sources, and previous pregnancy status.

RESULTS: The most common GTD types were hydatidiform mole (106, 75.7%), invasive mole (32, 22.9%), choriocarcinoma (1, 0.7%), and placental site trophoblastic tumor (1, 0.7%). GTD incidence was 8.5 in 1,000 deliveries. Most patients originated from the coastal region (East district), which includes the state capital (77.9%). The 20–34 age group predominated (65%). Education level (67.9% attended elementary school only) and employment rate (42.9%) were low. Secondary hospitals were the principal source of referral (84.3%), followed by self-referrals (15.7%). Regarding previous pregnancy status, 42.1% (n=59) had had term pregnancy, 39.3% (n=55) no pregnancy, 15% (n=21) miscarriage, and 0.7% (n=1) ectopic pregnancy; 4 patients (2.9%) had previous hydatidiform mole.

CONCLUSION: GTD predominated in the peak fertility age group and among
patients of unfavorable sociodemographic status.
Keywords:  demographics, geographical distribution, gestational trophoblastic disease
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