June 30th, 2022

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Massive Anterior Chest Wall Metastasis of Ovarian Cancer and Prolonged Survival After Treatment: A Case Report
Authors:  Tai-Jan Chiu, M.D., Yi-Ju Chen, M.D., and Cheng-Hua Huang, M.D.
BACKGROUND: Although previously uncommon, distant metastases of ovarian cancer are now observed with increasing frequency. Late-appearing metastases to the chest wall, however, are extremely rare; management is controversial and the prognosis is poor.

CASE: A 51-year-old woman presented with a massive metastatic tumor of the anterior chest wall 10 years after receiving total abdominal hysterectomy and bilateral salpingo-oophorectomy for primary ovarian cancer. The extremely large size of the tumor precluded surgical resection. Following successful chemotherapy and local irradiation, however, this patient has achieved long-term survival.

CONCLUSION: This report is the first to describe a case of a massive, inoperable chest wall tumor developing as a late metastasis of ovarian cancer. Systemic chemotherapy combined with local irradiation represents effective treatment for such unusual cases. (J Reprod Med 2008;53: 373-377)
Keywords:  chest wall tumor, metastasis, ovarian cancer, platinum-based chemotherapy
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