April 4th, 2020

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Relationship Between Endometriosis Pain and Anxiety or Depression: A Preliminary Study
Authors:  Yongping Zhang, M.M.
  OBJECTIVE: To investigate the relationship between endometriosis pain and anxiety or depression.

STUDY DESIGN: Visual analogue scale (VAS), Self- Rating Anxiety Scale (SAS), and Self-Rating Depression Scale (SDS) scores were evaluated and compared between group A (with endometriosis) and group B (without endometriosis). Moreover, in group A, 3 subtypes of endometriosis—
peritoneum, ovary, and deeply infiltrative endometriosis (DIE)—were analyzed respectively.

RESULTS: The VAS score of pelvic pain, dysmenorrhea, and dyspareunia of group A was higher than that of group B, and the corresponding scores of SAS and SDS were also significantly higher than those of group B (p<0.05). In comparing the 3 subdivided types, the VAS mean score of peritoneum type was significantly higher than DIE type and ovary type in pelvic pain and dyspareunia but not dysmenorrhea (p<0.05). There were no significant differences of SAS and SDS among the 3 subtypes (p>0.05).

CONCLUSION: Pelvic pain is more severe in endometriosis patients than in non-endometriosis patients, and anxiety and depression are common in endometriosis. Endometriosis pain and anxiety or depression are closely related and affect each other. Therefore, the simultaneous treatment of endometriosis, pain, and psychological morbidity is particularly important.
Keywords:  anxiety, chronic pain/psychology, depression, dyspareunia, emotion regulation, endo­metriosis, health­-related quality of life, pain, pelvic pain, psychiatric status rating scales, quality of life, psychological stress
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