April 4th, 2020

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Impact of Hysteroscopic Polypectomy on Pregnancy Outcomes of in Vitro Fertilization
Authors:  Man Wa Lui, M.B.B.S., Sofie S. F. Yung, M.B.B.S., Jennifer K. Y. Ko, M.B.B.S., Raymond H. R. Li, M.B.B.S., M.Med.Sc., and Ernest H. Y. Ng, M.B.B.S., M.D.
  OBJECTIVE: Endometrial polyps are commonly found in infertile women, but the impact of hysteroscopic polypectomy on in vitro fertilization (IVF) pregnancy outcomes was unclear. We aim to compare IVF preg­ nancy outcomes following hysteroscopic polypectomy to those with a normal uterine cavity.

STUDY DESIGN: Retro­ spective chart review of all women undergoing saline sonohysterogram prior to first IVF cycle from January 2012 to December 2013, in a university affiliated hos­pital.

RESULTS: A total of 715 women had saline sono­hysterogram during the study period, and endometrial polyps were identified in 65 with confirmation by hysteroscopy; 639 women had a normal uterine cavity. The positive predictive value of saline sonohysterogram was 97.0%, and the incidence was 9.1%. There were no differences in demographic parameters between women having hysteroscopic polypectomy and those with a normal uterine cavity. Clinical pregnancy rate (29.2% vs. 33.0% in women with hysteroscopic polypectomy and normal uterine cavity, respectively, p=0.535) and live birth rate (24.6% vs. 24.6% in women with hys­teroscopic polypectomy and normal uterine cavity, respectively, p=0.841) were similar.

CONCLUSION: Women having hysteroscopic polypec­tomy achieved similar IVF pregnancy outcomes when compared to those with a normal uterine cavity con­firmed by saline sonohys­terogram.
Keywords:  endometrial polyp, hysteroscopy, invitro fertilization, infertil­ity, pregnancy outcome
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