August 23rd, 2019

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Twin Delivery in a Patient with Swyer Syndrome: A Case Report
Authors:  GuoHua Li, M.D., JingYu Shao, Ph.D., ShiHua Bao, Ph.D., and ShengMing Ruan, M.D.
BACKGROUND: Swyer syndrome is one of the rarest causes of amenorrhea. Through sex hormonal cyclic replacement therapy, patients with Swyer syndrome can manifest normal menstruation and secondary sex characteristics. Few cases of pregnancy in patients with Swyer syndrome have been reported.

CASE: A 29-year-old woman with Swyer syndrome achieved a twin pregnancy by oocyte donation and IVF-ET and gave birth by cesarean section.

CONCLUSION: With adequate and appropriate hormonal therapy, the uterus of 46,XY patients can develop to the point of allowing pregnancy and delivery following embryo transfer.
Keywords:  46,XY gonadal dysgenesis; amenorrhea; cesarean section; embryo transfer; oocyte donation; pregnancy, twin; in-vitro fertilization; Swyer syndrome
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