August 23rd, 2019

A full text version of this article is available.
To access article obtain online access here or login
Blood Contaminated Amniotic Fluid and the Lamellar Body Count Fetal Lung Maturity Test
Authors:  Kevin C. Visconti, M.D., Craig V. Towers, M.D., Mark D. Hennessy, M.D., Bobby C. Howard, M.D., Stephanie Porter, W.H.N.P., and Beth Weitz, W.H.N.P.
  OBJECTIVE: To determine if maternal blood contamination falsely elevates the lamellar body count fetal lung maturity test.

STUDY DESIGN: Fifty mothers undergoing amniocentesis for fetal lung maturity consented to participation in the study. For each participant a blood-contaminated sample using the patient’s own blood was run in tandem with the noncontaminated sample used for clinical practice.

RESULTS: Of the 50 study patient samples the lamellar body count decreased by ≥3,000/μL in 33 (66%) and remained unchanged in 16 (32%). In only 1 case did the value increase—the actual result of 37,000/μL increased to 44,000/μL, both of which exceeded the mature level in our institution.

CONCLUSION: Maternal blood contamination of amniotic fluid does not falsely increase the lamellar body count in 98% of cases. The result was falsely lowered in 2 out of 3 cases. Therefore, a mature lamellar body count test result in a blood-contaminated sample is reliable.
Keywords:  amniocentesis, fetal lung maturity testing, lamellar body count, neonatal respiratory distress syndrome
  Acrobat Reader 7.0 is recommended to properly view and print the article.
Reader can be downloaded from