April 8th, 2020

A full text version of this article is available.
To access article obtain online access here or login
Direct Injection of Vasopressin During Hysteroscopic Myomectomy: A Case Report
Authors:  M. Brigid Holloran-Schwartz, M.D., Kallie Harrison, M.D., and Richard Gimpelson, M.D.
BACKGROUND: Hysteroscopic myomectomy is the ideal procedure for symptomatic women with submucosal fibroids who desire to preserve their fertility. Vascular myomas can limit visualization when a mechanical morcellator is used. Injection of a dilute vasopressin solution has been shown to decrease blood loss during laparoscopic myomectomy. To date, direct injection of a dilute vasopressin during hysteroscopic myomectomy has not been described.

CASE: Our first patient\'s hysteroscopic myomectomy of a vascular submucosal myoma had to be terminated before complete resection due to impaired visualization and maximum fluid overload. During a subsequent patient\'s procedure, direct injection of a dilute vasopressin through the operative port decreased intraoperative bleeding and enabled complete resection.

CONCLUSION: Injecting a dilute vasopressin solution directly into a vascular submucosal myoma during hysteroscopic resection can assist with hemostasis and visualization, enabling complete resection.
Keywords:  hysteroscopic myomectomy, laparoscopic myomectomy, mechanical morcellator, myomectomy, myometrium, submucosal fibroid, submucosal myoma, uterine leiomyoma, vasopressin
  Acrobat Reader 7.0 is recommended to properly view and print the article.
Reader can be downloaded from