June 18th, 2018

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Use of Clomiphene Citrate in the University of Utah Community Clinics
Authors:  Joseph B. Stanford, M.D., M.S.P.H., Jared C. Martin, M.D., Mark Gibson, M.D., Elisabeth Birdsall, Pharm.D., and Diana I. Brixner, Ph.D.
  OBJECTIVE: To determine patterns of usage of clomiphene citrate (CC) by primary care providers (obstetrician-gynecologists, family physicians, and other providers) within University of Utah Community Clinics.

STUDY DESIGN: We performed a retrospective chart review (n=79) and follow-up telephone survey of patients (n=43) who were prescribed CC in the University of Utah Community Clinics in 2006.

RESULTS: Most women who were prescribed CC had appropriate indications for therapy (65% with a diagnosis related to irregular menses and 33% with a diagnosis of female infertility), but there was variable and inconsistent monitoring of ovulation (much of which was apparently initiated by the patients). In the interview, 24 of the women (56%) said they would be fine having twins, and 14 (33%) said they would prefer to have twins if possible.

CONCLUSION: In this primary care setting, clomiphene was prescribed for appropriate indications, but the monitoring of treatment could be improved. The preference of some patients for twin gestations represents a challenge for optimum clinical care and public health.
Keywords:  clomiphene, ovulation induction, patient monitoring, primary health care
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