September 2nd, 2014

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Title:
Imaging Features of Columnar Cell Lesions of the Breast
Authors:  Yeong Yi An, M.D., Sung Hun Kim, M.D., Bong Joo Kang, M.D., A. Won Lee, M.D., and Byung Joo Song, M.D.
  OBJECTIVE: To evaluate sonographic and mammographic findings of columnar cell lesions (CCLs) and to identify any specific imaging characteristics that may help in the differentiation of flat epithelial atypia from other CCLs.

STUDY DESIGN: We retrospectively reviewed a total of 28 CCLs in 26 patients. For each lesion medical records, the images and the pathological reports were reviewed.

RESULTS: CCLs presented as microcalcifications in 37% on mammography, and amorphous or fine pleomorphic microcalcifications were the usual mammographic findings. On sonography they presented as a mass in 71.4%, and an oval or irregular mass with an indistinct margin was the most common. Among 28 lesions 89.3% presented as suspicious microcalcifications or masses that warranted biopsies. There was no significant difference in the image features between flat epithelial atypia and columnar cell changes/ columnar cell hyperplasia.

CONCLUSION: CCLs usually present as microcalcifications or a mass suspicious for malignancy. Thus, percutaneous needle biopsy or excisional biopsy should be required for diagnosis.
Keywords:  breast; breast ultrasonography; calcification, physiologic; mammography
   
   
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