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Title: |
Pap Smears with Reactive Cellular Changes: A Prospective Study | |||||||||||||||||||
| Authors: | Dah-Ching Ding, M.D., Senzan Hsu, M.D., Sidney S. Chen, M.D., and Yung-Hsiang Hsu, M.D. | |||||||||||||||||||
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OBJECTIVE: To determine the prevalence of cervical dysplasia and cervical cancer in women with atypical squamous cells (ASCs).
STUDY DESIGN: A prospective study was conducted at Buddhist Tzu Chi General Hospital from January 1 to September 30, 2003. The primary measurement was cervical dysplasia and the secondary one, cervical cancer. Forty-nine women with Pap smears showing reactive cellular changes were enrolled. All patients underwent colposcopy and biopsy. Endocervical curettage (ECC) was performed before colposcopy. All specimens were reviewed by a pathologist. RESULTS: Histologic results revealed normal findings in 30 (61%), mild dysplasia in 9 (18.3%), moderate dysplasia in 1 (2%), severe dysplasia in 2 (4%), squamous cell carcinoma in 2 (4%), adenocarcinoma in 1 (2%) and benign lesions in 4 (8.1%). CONCLUSION: Among the subjects with cervical ASCs, 30% and 6% with cervical dysplasia and cervical cancer, respectively, were identified. Colposcopically directed biopsy and ECC are warranted in women with ASC. (J Reprod Med 2007;52:938-940) |
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| Keywords: | cervical intraepithelial neoplasia, cervix cancer, Papanicolaou smear, reactive cervical changes | |||||||||||||||||||
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